Amy Schumer Opens Up About Her Weight Loss Journey: “I Just Wanted to Be Real About It”

Amy Schumer is showing off her new look — and fans can’t stop talking about it.

The 44-year-old actress and comedian turned heads this weekend after sharing a stunning new photo on Instagram from her Las Vegas trip with friends Alex Saks and Jillian Bell. Dressed in a chic Miu Miu button-down mini shirt dress and classic black heels, Schumer looked radiant, confident, and noticeably slimmer.

Ok legs for days!!” wrote Real Housewives of New Jersey star Margaret Josephs, while celebrity facialist Georgia Louise added, “Amy … legs need to come out more!!!” Producer Lee Daniels also chimed in, calling her “skinnnnnnny mommmmma.”

A Journey of Honesty and Transformation

Schumer has never been one to shy away from the truth. Over the past few years, she’s been candid about her health journey, including her experiences with weight loss medications like Ozempic and Mounjaro, as well as liposuction.

In a January interview on The Howard Stern Show, Schumer revealed she tried Ozempic nearly three years ago but had an intense reaction to it.

“I have this gene, GDF15, which makes you extremely prone to nausea,” she explained. “I was bedridden, vomiting, had no energy … I couldn’t even play ball with my son.”

The Trainwreck star admitted that while many people praise the medication for its results, the side effects weren’t worth it for her. “Other people take it and they’re all good — God bless them — but it wasn’t for me,” she said.

“Be Real With the People” — Amy’s Message About Transparency

Schumer has made it a personal mission to stay honest about the realities of weight loss in Hollywood. During an appearance on Watch What Happens Live with Andy Cohen in June 2023, she called out the lack of transparency among celebrities.

“Everyone’s been lying, saying, ‘Oh, I just eat smaller portions.’ Like, shut the f— up,” she said bluntly. “You’re on Ozempic or one of those things — or you got work done. Just stop. Be real with the people. When I got lipo, I said I got lipo.”

Her candidness struck a chord with fans who praised her for cutting through the filtered perfection of celebrity culture and speaking from a place of honesty.

Finding Balance and Feeling Better

Today, Amy Schumer says she’s finally found a routine that truly works for her body. The Inside Amy Schumer creator revealed earlier this year that she’s now using a combination of estrogen and progesterone for her perimenopause symptoms, alongside Mounjaro (a GLP-1 drug originally used for Type 2 diabetes but often prescribed for weight loss).

“My symptoms of being in perimenopause have disappeared. My hair is fuller, my skin is better, I have more energy,” Schumer shared on Instagram. “I’m having a really good experience, and I wanted to keep it real with you about that.”

Her openness continues to inspire fans who appreciate her refusal to hide behind unrealistic beauty standards.

Why Amy’s Story Matters

Schumer’s approach to health and transparency stands out in an industry that often rewards silence and perfection. She’s not just celebrating a physical transformation — she’s championing body honesty, self-acceptance, and the importance of finding what works for you.

As she told The Hollywood Reporter,

“Everybody on camera is doing this s—. I just wanted to be real about it.”

And that authenticity is exactly why Amy Schumer continues to be one of Hollywood’s most relatable and empowering voices — a star unafraid to look the world in the eye and say, “This is me.”